Will Diego Pavia lead Vanderbilt football past Virginia Tech again? Our prediction

Vanderbilt football is set to head to its first road game of 2025 when it takes on Virginia Tech in Blacksburg.

The Commodores (1-0) defeated Charleston Southern, 45-3, in the opener. The Hokies (0-1) lost to South Carolina, 24-11, in a neutral-site game.

Vanderbilt defeated Virginia Tech in overtime at FirstBank Stadium to begin the 2024 season.

Both teams return their starting quarterbacks, with the Commodores retaining Diego Pavia and the Hokies returning Kyron Drones.

The game will be at 6:30 p.m. CT on ACC Network from Lane Stadium.

Here is our prediction for the game:

Vanderbilt vs Virginia Tech prediction

Vanderbilt is a step above Virginia Tech from a talent standpoint, and this could be a showcase game for Pavia and Eli Stowers. Bet on special teams to make a difference for the Commodores, too.

Vanderbilt vs Virginia Tech scouting report

Why Vanderbilt has an advantage: Vanderbilt is more talented than Virginia Tech and won the matchup between the two teams a year ago. Pavia and Stowers are a better offensive duo than what Virginia Tech has, and Pavia’s running ability could help negate the Hokies’ defensive line. Virginia Tech allowed a punt return touchdown to the Gamecocks, which is something the Commodores could take advantage of.

Why Virginia Tech has an advantage: The Hokies are at home with a sellout crowd, and that always counts for something. Virginia Tech has a strong defensive line, which could cause problems for a Vanderbilt offensive line that lacks depth. While they are expected to still play, the Commodores have a few offensive players dealing with injuries that could impact their performance.

Vanderbilt vs Virginia Tech injury updates

Vanderbilt tight end Cole Spence and wide receiver Junior Sherrill are both probable after suffering injuries against Charleston Southern. Offensive lineman Gunner Givens (lower body) is questionable.